Based on my experience, it would be a possible option. You, however, need to show a sound reason why your wife does so (i.e., as your wife is interested in becoming a nurse, she needs to take a TOEFL / develop more fluent conversational skills >>> if your wife plans to enroll in any Kaplan class or language course).

I forgot to mention that the timing is critical. If you were already laid off, meaning that your H as well as your wife’s are no longer valid, you are not able to change your status in that COS (change of status) must begin with a valid non-immigrant status…